That is what runs all arcade programs. If you are running Windows, download the *.exe (second in the download list).
This program is all you really need. However, the interface isn't graphical by default. I recommend running MAMEUI but there are tons of "front ends" that let you just click and run a game: www.mameui.info/
Whole trick is to make sure you know where you are installing things. You have to get any ROM into the folder called "rom" (duh). Do it properly and you should see an arcade machine icon in your MAMEUI folder. Shoot down to Tron and double-click. If you remember the original game, a joystick for your computer is the best way to run it.
Like I said, though, you are on your own to supply the blacklights.